Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266390 | 1.00 | CA2 (0.57) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL3266393 | 1.00 | CA2 (0.57) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL31106544 | 0.83 | CA2 (0.59) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL1131871 | 0.82 | CA2 (0.68) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL1131664 | 0.82 | — | — | |
| SCHEMBL14360108 | 0.82 | CA2 (0.81) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL5480350 | 0.81 | CA2 (0.57) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL31474868 | 0.81 | CA2 (0.43) | CA2MAPK1FFAR4ACACBACACA | |
| Cyclohexane SCHEMBL7889081 | 0.79 | CA2 (0.59) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL16223957 | 0.79 | CA2 (0.70) | CA2MAPK1FFAR4FFAR1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633779-B1 | OXIDOREDUCTASE FROM PICHIA CAPSULATA | IEP GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1685248-B1 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | IEP GMBH (DE) | 2010-06-09 | — | — | EP | disclosed |
| US-20070243594-A1 | Oxidoreductase from Pichia Capsulata | IEP GMBH (DE) | 2007-10-18 | — | — | US | disclosed |
| EP-1685248-A2 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | IEP GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049816-A2 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | JUELICH ENZYME PRODUCTS GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |