Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.72 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22467564 | 0.91 | LPAR1 (0.88) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL22467571 | 0.91 | LPAR1 (0.88) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL22467451 | 0.91 | LPAR1 (0.88) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL32671669 | 0.90 | LPAR1 (0.82) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL32671665 | 0.89 | LPAR1 (0.60) | LPAR1SLCO1B1LMNASMN1; SMN2KLKB1 | |
| SCHEMBL32671652 | 0.87 | LPAR1 (0.57) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL32671641 | 0.87 | LPAR1 (0.63) | LPAR1SLCO1B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29869250 | 0.87 | LPAR1 (0.74) | LPAR1SLCO1B1CTSLCTSSCTSK | |
| SCHEMBL32671673 | 0.86 | LPAR1 (0.61) | LPAR1SLCO1B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL32671654 | 0.86 | LPAR1 (0.60) | LPAR1SLCO1B1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728210-B1 | ISOXAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-02-11 | — | — | EP | claimed |