Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.60 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22467600 | 0.90 | LPAR1 (0.75) | LPAR1SLCO1B1AKR1C3SLC6A9HPGD | |
| SCHEMBL32671664 | 0.89 | LPAR1 (0.72) | LPAR1SLCO1B1KLKB1SLC6A9LMNA | |
| SCHEMBL32671641 | 0.85 | LPAR1 (0.63) | LPAR1SLCO1B1SLC6A9EPHX1HPGD | |
| SCHEMBL32671653 | 0.83 | LPAR1 (0.56) | LPAR1SLCO1B1SLC6A9HPGDLMNA | |
| SCHEMBL32671673 | 0.82 | LPAR1 (0.61) | LPAR1SLCO1B1SLC6A9LMNASMN1; SMN2 | |
| SCHEMBL32671681 | 0.81 | LPAR1 (0.58) | LPAR1SLCO1B1SLC6A9HPGDLMNA | |
| SCHEMBL32671654 | 0.81 | LPAR1 (0.60) | LPAR1SLCO1B1SLC6A9LMNASMN1; SMN2 | |
| SCHEMBL32671669 | 0.80 | LPAR1 (0.82) | LPAR1SLCO1B1LMNASMN1; SMN2ACACB | |
| SCHEMBL22467571 | 0.80 | LPAR1 (0.88) | LPAR1SLCO1B1AKR1C3SLC6A9GAA | |
| SCHEMBL22467559 | 0.80 | LPAR1 (0.76) | LPAR1SLCO1B1SLC6A9TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728210-B1 | ISOXAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-02-11 | — | — | EP | claimed |