Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 7/20 | 0.45 |
| ▸ | REN | P00797 | 4/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510749 | 0.91 | ACE (0.53) | ACERENKDM4EF2LMNA | |
| SCHEMBL29630627 | 0.89 | ACE (0.49) | XIAPACERENNTSR2NTSR1 | |
| SCHEMBL9347620 | 0.88 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL9347633 | 0.88 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL29823571 | 0.88 | XIAP (0.47) | XIAPACERENNTSR2NTSR1 | |
| SCHEMBL31171909 | 0.87 | XIAP (0.46) | XIAPACERENKDM4EF2 | |
| Hydrochloric Acid SCHEMBL9348537 | 0.87 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| Hydrochloric Acid SCHEMBL9348527 | 0.87 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| SCHEMBL23260256 | 0.86 | XIAP (0.55) | XIAPACERENKMT2AL3MBTL1 | |
| SCHEMBL31202557 | 0.86 | XIAP (0.55) | XIAPACERENKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042858-A1 | Modified IgG1 Fc Domains and Anti-CD40 Domain Antibody Fusions Therewith | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042858-A1 | Modified IgG1 Fc Domains and Anti-CD40 Domain Antibody Fusions Therewith | CD40LG, CD40, FCGR1A | XIAP 1890/4885ACE 3666/4885REN 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.