SCHEMBL32673154

SCHEMBL32673154

Brc1ccnc2c1ccc1c(N3CCCC3)ccnc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
HTT P42858 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MITF O75030 1/20 0.50
ALOX15 P16050 3/20 0.49
PKM P14618 1/20 0.49
CASP1 P29466 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CHKA P35790 1/20 0.48
NCF1 P14598 4/20 0.40
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23085094 0.89 MAPT (0.58) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL23085137 0.88 CHKA (0.58) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL32672801 0.80 HTT (0.34) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL32673044 0.80 PKM (0.56) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL2206337 0.78 CCR1 (0.50) MAPTHTTSMN1; SMN2ALOX15LMNA
SCHEMBL23085093 0.74 PIK3CA (0.58) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL29380705 0.73 MAPT (0.61) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL5409114 0.72 PKM (0.68) MAPTSMN1; SMN2ALOX15PKMCASP1
SCHEMBL29380460 0.72 MAPT (0.59) MAPTHTTSMN1; SMN2MITFALOX15
SCHEMBL15161240 0.71 SMN1; SMN2 (0.58) MAPTHTTSMN1; SMN2MITFALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042756-A1 Organic Compound And Method For Synthesizing The Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042756-A1 Organic Compound And Method For Synthesizing The Same MRPS22, H1-2, H1-0 MAPT 4497/4885HTT 1991/4885SMN1; SMN2 4141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.