Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.33 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 6/20 | 0.32 |
| ▸ | GLB1 | P16278 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346594 | 0.78 | GBA1 (0.41) | GBA1MAN1B1MAN2A1FUCA1GLB1 | |
| SCHEMBL2346601 | 0.78 | GBA1 (0.41) | GBA1MAPTUSP2ALDH1A1HPGD | |
| SCHEMBL1873751 | 0.75 | GBA1 (0.43) | GBA1FUCA1GLB1 | |
| SCHEMBL2353766 | 0.73 | GBA1 (0.38) | GBA1FUCA1GLB1PLA2G2APLA2G10 | |
| SCHEMBL2353762 | 0.73 | GBA1 (0.38) | GBA1FUCA1GLB1PLA2G2APLA2G10 | |
| SCHEMBL1861356 | 0.72 | GBA1 (0.43) | GBA1MAN1B1MAN2A1FUCA1GLB1 | |
| SCHEMBL3267391 | 0.72 | GBA1 (0.37) | GBA1MAPTUSP2ALDH1A1HPGD | |
| SCHEMBL3267395 | 0.69 | PLA2G10 (0.40) | GBA1MAPTUSP2ALDH1A1HPGD | |
| SCHEMBL1861352 | 0.69 | HTR7 (0.40) | GBA1FUCA1 | |
| SCHEMBL1861358 | 0.68 | MKNK1 (0.41) | GBA1FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029313-A1 | ANTIINFECTIVE COMPOUNDS | SUMMIT CORPORATION PLC. (GB) | 2010-03-18 | — | — | WO | disclosed |