Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3268777 | 0.99 | DHFR (0.78) | DHFR | |
| SCHEMBL31155868 | 0.90 | DHFR (0.90) | DHFR | |
| SCHEMBL31155948 | 0.89 | DHFR (0.88) | DHFR | |
| SCHEMBL3268406 | 0.89 | DHFR (1.00) | DHFR | |
| Hydrochloric Acid SCHEMBL3268093 | 0.88 | DHFR (0.98) | DHFR | |
| SCHEMBL3268862 | 0.88 | DHFR (0.66) | DHFR | |
| SCHEMBL31155826 | 0.87 | DHFR (0.96) | DHFR | |
| Hydrochloric Acid SCHEMBL3273826 | 0.87 | DHFR (0.65) | DHFR | |
| SCHEMBL31155827 | 0.87 | DHFR (0.68) | DHFR | |
| SCHEMBL31155832 | 0.85 | DHFR (0.94) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194985-B1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2019-02-20 | — | — | EP | claimed |
| US-8530491-B2 | Antimalarial compounds with flexible side-chains | MEDICINES FOR MALARIA VENTURE (MMV) (CH) | 2013-09-10 | — | — | US | claimed |
| EP-3546452-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MMV Medicines for Malaria Venture (CH) | 2019-10-02 | — | — | EP | disclosed |
| EP-2194985-B1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2019-02-20 | — | — | EP | disclosed |
| US-8530491-B2 | Antimalarial compounds with flexible side-chains | MEDICINES FOR MALARIA VENTURE (MMV) (CH) | 2013-09-10 | — | — | US | disclosed |
| EP-2194985-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | Medicines for Malaria Venture (CH) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009048957-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE (CH) | 2009-04-16 | — | — | WO | disclosed |
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | DHFR, FPGS, DHODH | DHFR 1/4885LMNA 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.