Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20984065 | 0.87 | GAA (0.67) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11207257 | 0.84 | ALDH1A1 (0.63) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL10433483 | 0.83 | ALDH1A1 (0.63) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL175272 | 0.81 | MEN1 (0.71) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL113558 | 0.81 | MEN1 (0.71) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL12188090 | 0.81 | ALDH1A1 (0.59) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL2951524 | 0.80 | ALDH1A1 (0.58) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL2937028 | 0.79 | ALDH1A1 (0.68) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL7573420 | 0.79 | ALDH1A1 (0.59) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL28888390 | 0.78 | ALDH1A1 (0.70) | GAAALDH1A1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193123-A1 | NOVEL BENZIMIDAZOL-2-YL-ALKYLAMINES AND THE USE THEREOF AS MICROBICIDAL AGENTS | EMC microcollections GmbH (DE) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009019014-A1 | NOVEL BENZIMIDAZOL-2-YL-ALKYLAMINES AND THE USE THEREOF AS MICROBICIDAL AGENTS | EMC MICROCOLLECTIONS GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |