SCHEMBL32675769

SCHEMBL32675769

CCCCc1nc2c(N)nnc(OC(C)C)c2n1Cc1ccc(CN(Cc2ccc(OC)cc2)C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.54
TLR8 Q9NR97 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29840923 0.91 TLR7 (0.61) TLR7TLR8
SCHEMBL32675763 0.88 TLR7 (0.59) TLR7
SCHEMBL29840960 0.84 TLR7 (0.61) TLR7TLR8
SCHEMBL29109809 0.84 TLR7 (0.51) TLR7TLR8
SCHEMBL29109808 0.84 TLR7 (0.51) TLR7TLR8
SCHEMBL29109909 0.84 TLR7 (0.59) TLR7TLR8
SCHEMBL29840802 0.84 TLR7 (0.59) TLR7TLR8
SCHEMBL29840801 0.83 TLR7 (0.68) TLR7TLR8
SCHEMBL29841009 0.83 TLR7 (0.58) TLR7TLR8
SCHEMBL29109822 0.83 TLR7 (0.60) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288438-B1 DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-02-18 EP claimed