SCHEMBL32675763

SCHEMBL32675763

CCCCc1nc2c(N)nnc(OC(C)C)c2n1Cc1ccc(CN(Cc2ccc(NC(C)=O)cc2)C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32675769 0.88 TLR7 (0.54) TLR7
SCHEMBL29109812 0.85 TLR7 (0.56) TLR7
SCHEMBL29109816 0.85 TLR7 (0.56) TLR7
SCHEMBL27217343 0.84 TLR7 (0.53) TLR7
SCHEMBL29840960 0.83 TLR7 (0.61) TLR7
SCHEMBL32675771 0.81 TLR7 (0.55) TLR7
SCHEMBL29109822 0.81 TLR7 (0.60) TLR7
SCHEMBL32675801 0.81 TLR7 (0.61) TLR7
SCHEMBL29109848 0.80 TLR7 (0.57) TLR7
Hydrochloric Acid SCHEMBL30663254 0.80 TLR7 (0.60) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288438-B1 DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-02-18 EP claimed