SCHEMBL32675784

SCHEMBL32675784

CCC[S+]([O-])c1nc2c(OC(C)C)nnc(N)c2[nH]1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.34
TLR7 Q9NYK1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32675809 0.73 TLR8 (0.36) TLR8TLR7
SCHEMBL32675776 0.72 TLR8 (0.43) TLR8TLR7
SCHEMBL29109851 0.66 TLR7 (0.39) TLR8TLR7
SCHEMBL29840892 0.63 TLR8 (0.41) TLR8TLR7
Hydrochloric Acid SCHEMBL29840678 0.62 TLR8 (0.40) TLR8TLR7
SCHEMBL32675792 0.62 CDK2 (0.51)
SCHEMBL30663232 0.57 TLR7 (0.40) TLR8TLR7
SCHEMBL29109854 0.57 TLR7 (0.51) TLR8TLR7
SCHEMBL29109934 0.57 TLR7 (0.40) TLR8TLR7
SCHEMBL30663434 0.56 CDK2 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288438-B1 DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-02-18 EP claimed