Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32675776 | 0.75 | TLR8 (0.43) | TLR8TLR7ALDH1A1GAAMAPT | |
| SCHEMBL32675784 | 0.73 | TLR8 (0.34) | TLR8TLR7 | |
| SCHEMBL29840892 | 0.66 | TLR8 (0.41) | TLR8TLR7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29840678 | 0.65 | TLR8 (0.40) | TLR8TLR7ALDH1A1 | |
| SCHEMBL32675792 | 0.64 | CDK2 (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29267360 | 0.63 | ALDH1A1 (0.44) | HTTALDH1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL12820579 | 0.62 | HTT (0.46) | HTTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL30663232 | 0.60 | TLR7 (0.40) | TLR8TLR7 | |
| SCHEMBL22522025 | 0.59 | XDH (0.55) | HTTALDH1A1MCL1CXCR1CXCR2 | |
| SCHEMBL29109934 | 0.59 | TLR7 (0.40) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288438-B1 | DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2026-02-18 | — | — | EP | claimed |