SCHEMBL32677383

SCHEMBL32677383

N#C/C(=C\c1cn(Cc2cccc(C(F)(F)F)c2)c2ncccc12)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 4/20 0.57
▸ SNCA P37840 4/20 0.57
▸ ENPP2 Q13822 1/20 0.46
▸ ELANE P08246 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ KDM4C Q9H3R0 1/20 0.40
▸ SIRT2 Q8IXJ6 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ GLA P06280 1/20 0.40
▸ HTR6 P50406 1/20 0.39
▸ PARP1 P09874 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25424902 1.00 APP (0.57) APPSNCAENPP2ELANEALDH1A1
SCHEMBL31169581 1.00 APP (0.57) APPSNCAENPP2ELANEALDH1A1
SCHEMBL28377102 0.93 APP (0.57) APPSNCAENPP2ELANEALDH1A1
SCHEMBL20603144 0.93 APP (0.57) APPSNCAENPP2ELANEALDH1A1
SCHEMBL26116453 0.90 SNCA (0.60) APPSNCAENPP2ELANEALDH1A1
SCHEMBL27440758 0.89 SNCA (0.57) APPSNCAENPP2ALDH1A1LMNA
SCHEMBL31050160 0.89 APP (0.55) APPSNCAENPP2ALDH1A1LMNA
SCHEMBL26552405 0.89 APP (0.52) APPSNCAENPP2ELANEALDH1A1
SCHEMBL27440285 0.89 APP (0.52) APPSNCAENPP2ELANEALDH1A1
SCHEMBL27440401 0.89 APP (0.55) APPSNCAENPP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559490-B2 Compositions and methods for modulating hair growth THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559490-B2 Compositions and methods for modulating hair growth PC, MTCH2, MPC2 APP 2307/4885SNCA 4595/4885ENPP2 4531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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