Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133939 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL31332619 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL31076255 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL5675799 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL3420686 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL15797923 | 1.00 | KDM1A (0.53) | KDM1AKDM1BFFAR1HTR2CHTR2B | |
| SCHEMBL30636931 | 0.84 | DRD2 (0.44) | KDM1AKDM1BFFAR1MEN1KMT2A | |
| SCHEMBL26186779 | 0.84 | DRD2 (0.44) | KDM1AKDM1BFFAR1MEN1KMT2A | |
| SCHEMBL26186789 | 0.84 | DRD2 (0.44) | KDM1AKDM1BFFAR1MEN1KMT2A | |
| SCHEMBL26186918 | 0.84 | DRD2 (0.44) | KDM1AKDM1BFFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026041636-A1 | MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2026-02-26 | — | — | WO | disclosed |