SCHEMBL32678465

SCHEMBL32678465

CCSc1cc(C2CC2)cnc1C#N

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.33
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678469 1.00 ALDH1A1 (0.36) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL20848148 1.00 ALDH1A1 (0.36) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL32678467 1.00 ALDH1A1 (0.36) ALDH1A1MAPTHPGDTDP1MAPK1
SCHEMBL17504803 0.78 SMN1; SMN2 (0.36) ALDH1A1MAPTHPGDTDP1KDM4E
SCHEMBL20848120 0.78 KDM4E (0.33) KDM4E
SCHEMBL22272004 0.77 KDM4E (0.33) KDM4E
SCHEMBL20867084 0.76 SMN1; SMN2 (0.40) ALDH1A1MAPTHPGDMAPK1MEN1
SCHEMBL23642509 0.75 MAPK1 (0.36) ALDH1A1HPGDMAPK1MEN1KMT2A
SCHEMBL17514093 0.75 MAPK1 (0.36) ALDH1A1MAPTHPGDMAPK1MEN1
SCHEMBL20867390 0.75 MAPK1 (0.36) ALDH1A1HPGDMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041700-A1 PROCESS FOR PREPARING OXAZOLE COMPOUNDS BASF SE (DE) 2026-02-26 WO disclosed