SCHEMBL32678740

SCHEMBL32678740

Cc1ncsc1C(CN)C(C)O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
PKM P14618 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
P2RX7 Q99572 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678739 1.00 KDM4E (0.34) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL32678743 1.00 KDM4E (0.34) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL23384732 0.80 KDM4E (0.37) KDM4EPKMMEN1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL32678745 0.79 KDM4E (0.37) KDM4EPKMMEN1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL32678742 0.79 KDM4E (0.37) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL21401004 0.78 KDM4E (0.37) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL8683323 0.77 KDM4E (0.43) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL20604242 0.76 APLNR (0.41) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL20604241 0.76 APLNR (0.41) KDM4EPKMMEN1ALDH1A1LMNA
SCHEMBL15150557 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041663-A1 P2X7 RECEPTOR ANTAGONISTS BREYE THERAPEUTICS APS (DK) 2026-02-26 WO disclosed