Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | BCR | P11274 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679381 | 0.90 | TTBK1 (0.44) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679401 | 0.89 | TTBK1 (0.44) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679397 | 0.88 | TTBK1 (0.44) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679402 | 0.86 | TTBK1 (0.47) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679373 | 0.85 | TTBK1 (0.45) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679394 | 0.82 | EGFR (0.52) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679393 | 0.82 | EGFR (0.52) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679398 | 0.81 | PIP4K2A (0.48) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679384 | 0.81 | MAPT (0.52) | MAPTTP53TTBK1TTBK2KDR | |
| SCHEMBL32679395 | 0.81 | TTBK1 (0.45) | MAPTTP53TTBK1TTBK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120424083-B | Pyrrolo pyrimidine compound and preparation method and application thereof | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | 2026-02-27 | — | — | CN | disclosed |