SCHEMBL32679384

SCHEMBL32679384

Cc1ccc(C(=O)N(N)C(=O)n2ccc3c(Nc4ccc(Oc5ccccc5)cc4)ncnc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
TP53 P04637 4/20 0.52
LMNA P02545 1/20 0.47
TTBK1 Q5TCY1 3/20 0.45
TTBK2 Q6IQ55 3/20 0.45
KDR P35968 1/20 0.43
TEK Q02763 1/20 0.43
ABL1 P00519 2/20 0.42
BCR P11274 2/20 0.42
EGFR P00533 4/20 0.41
RIPK2 O43353 1/20 0.41
EPHB2 P29323 1/20 0.41
ERBB2 P04626 3/20 0.41
ERBB4 Q15303 2/20 0.41
JAK3 P52333 1/20 0.41
PIP4K2A P48426 2/20 0.40
PIK3CG P48736 2/20 0.40
F9 P00740 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679398 0.93 PIP4K2A (0.48) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679402 0.85 TTBK1 (0.47) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679403 0.84 TTBK1 (0.44) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679373 0.84 TTBK1 (0.45) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679397 0.83 TTBK1 (0.44) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679394 0.83 EGFR (0.52) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679393 0.83 EGFR (0.52) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679381 0.82 TTBK1 (0.44) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679395 0.82 TTBK1 (0.45) MAPTTP53LMNATTBK1TTBK2
SCHEMBL32679372 0.81 MAPT (0.43) MAPTTP53LMNATTBK1TTBK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120424083-B Pyrrolo pyrimidine compound and preparation method and application thereof 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) 2026-02-27 CN disclosed