SCHEMBL32682503

SCHEMBL32682503

C[C@H]1c2nn(C)c(-c3cc(F)c(F)c(F)c3)c2CCN1C(=O)c1cccc(-c2cnn(C)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 19/20 0.64
▸ CREBBP Q92793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21818338 1.00 MGLL (0.64) MGLLCREBBP
SCHEMBL32682463 0.87 MGLL (0.50) MGLL
SCHEMBL21818004 0.87 MGLL (0.50) MGLL
SCHEMBL21818368 0.87 MGLL (0.51) MGLL
SCHEMBL32682464 0.87 MGLL (0.51) MGLL
SCHEMBL32682534 0.84 MGLL (0.65) MGLL
SCHEMBL21818423 0.84 MGLL (0.65) MGLL
SCHEMBL21819345 0.84 MGLL (0.48) MGLL
SCHEMBL32682505 0.84 MGLL (0.48) MGLL
SCHEMBL21818274 0.84 MGLL (0.63) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856178-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 — — EP claimed
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