SCHEMBL32683807

SCHEMBL32683807

Nc1cncn1Cc1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 13/20 0.59
CYP11B2 P19099 13/20 0.59
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
CYP19A1 P11511 2/20 0.46
SLC2A1 P11166 1/20 0.45
IDO1 P14902 1/20 0.45
NFATC1 O95644 1/20 0.41
GSK3B P49841 1/20 0.41
DYRK1A Q13627 1/20 0.41
THRB P10828 1/20 0.41
MITF O75030 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
DBH P09172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1460583 0.80 CYP11B1 (0.51) CYP11B1CYP11B2SLC2A1IDO1RAB9A
Hydrochloric Acid SCHEMBL7851059 0.77 CYP11B1 (0.66) CYP11B1CYP11B2CYP19A1IDO1
SCHEMBL28174123 0.76 CYP11B1 (0.56) CYP11B1CYP11B2MAPTCYP19A1IDO1
SCHEMBL17544724 0.76 CYP11B1 (0.64) CYP11B1CYP11B2CYP19A1IDO1
Hydrochloric Acid SCHEMBL6925333 0.76 CYP11B1 (0.64) CYP11B1CYP11B2MAPTLMNACYP19A1
Hydrochloric Acid SCHEMBL17185367 0.76 CYP11B1 (0.68) CYP11B1CYP11B2MAPTLMNACYP19A1
SCHEMBL17544474 0.75 CYP11B1 (0.59) CYP11B1CYP11B2CYP19A1IDO1NFATC1
SCHEMBL765399 0.75 CYP11B1 (0.67) CYP11B1CYP11B2MAPTCYP19A1IDO1
SCHEMBL3823466 0.75 CYP11B1 (1.00) CYP11B1CYP11B2IDO1
SCHEMBL3914923 0.73 CYP11B1 (0.54) CYP11B1CYP11B2MAPTLMNACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R CYP11B1 1326/4885CYP11B2 1590/4885MAPT 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.