Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 16/20 | 0.78 |
| ▸ | BCHE | P06276 | 5/20 | 0.78 |
| ▸ | ACHE | P22303 | 5/20 | 0.78 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.78 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.78 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.78 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.78 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.78 |
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | THPO | P40225 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7547505 | 0.92 | CHRM2 (0.85) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL8138468 | 0.89 | CHRM2 (0.72) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL29456771 | 0.88 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9351001 | 0.88 | CHRM2 (0.73) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL31138865 | 0.88 | CHRM2 (0.93) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL11982296 | 0.88 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL4354687 | 0.88 | CHRM2 (0.73) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918396 | 0.87 | CHRM2 (0.79) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL31061008 | 0.86 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4913173 | 0.85 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | disclosed |
| CN-100439332-C | Novel thiourea derivatives and the pharmaceutical compositions containing thd same | PACFIC CORP (KR) | 2008-12-03 | — | — | CN | disclosed |
| CN-1418191-A | Novel thiourea derivatives and pharmaceutical compositions containing the same | PACFIC CORP (KR) | 2003-05-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | CHRM2 201/4885BCHE 26/4885ACHE 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.