SCHEMBL3268545

SCHEMBL3268545

C=CC(=O)OCCOC(=O)O

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.70
ALDH1A1 P00352 4/20 0.70
TP53 P04637 3/20 0.70
HIF1A Q16665 3/20 0.70
HSD17B10 Q99714 1/20 0.70
CYP3A4 P08684 2/20 0.62
HPGD P15428 1/20 0.56
THRB P10828 4/20 0.55
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.36
HCAR2 Q8TDS4 5/20 0.35
ATM Q13315 1/20 0.33
AKR1B10 O60218 1/20 0.32
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520880 0.93 TSHR (0.83) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8961963 0.91 TSHR (0.78) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL93462 0.89 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL30604742 0.89 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL25823302 0.89 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL25967152 0.88 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid SCHEMBL2687062 0.87 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL1165263 0.87 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL900042 0.87 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
Ammonia Solution, Strong SCHEMBL27352657 0.87 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579434-B1 Dialkyl peroxide, cross-linking composition containing the same, method for cross-linking, and electric power cable NOF CORP (JP) 1995-10-18 EP claimed
EP-0579434-A1 Dialkyl peroxide, cross-linking composition containing the same, method for cross-linking, and electric power cable NOF CORPORATION (JP) 1994-01-19 EP claimed
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-1548850-B1 WHITE LIGHT EMITTING DEVICE TOYODA GOSEI KK (JP) 2010-06-16 EP disclosed
US-7227190-B2 White light emitting device TOYODA GOSEI CO., LTD. (JP) 2007-06-05 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-20050253158-A1 White light emitting device TRIDONICATCO OPTOELECTRONICS GMBH (AT) 2005-11-17 US disclosed
EP-1548850-A1 WHITE LIGHT EMITTING DEVICE Toyoda Gosei Co., Ltd. (JP) 2005-06-29 EP disclosed
US-6890879-B2 Recording material and image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
US-20020183202-A1 Recording material and image forming method FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
EP-1254780-A2 Recording material and image forming method Fuji Photo Film Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-0381861-A2 Maleimide copolymer and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1990-08-16 EP disclosed
EP-0225102-B1 METHOD FOR PRODUCING A GRAFTED ETHYLENE-ACRYLIC ACID ESTER COPOLYMER NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1990-07-25 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
US-4753990-A USING A PEROXY GROUP CONTAINING BLOCK POLYMER NIPPON OIL AND FATS CO., LTD. (JP) 1988-06-28 US disclosed
EP-0225102-A1 Method for producing a grafted ethylene-acrylic acid ester copolymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-06-10 EP disclosed