SCHEMBL900042

SCHEMBL900042

C=CC(=O)OCCOC(=O)C=C.[SiH4]

nearest known ligand 0.80

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.80
ALDH1A1 P00352 7/20 0.80
TP53 P04637 3/20 0.80
HIF1A Q16665 3/20 0.80
HSD17B10 Q99714 1/20 0.80
CYP3A4 P08684 2/20 0.71
HPGD P15428 1/20 0.62
THRB P10828 4/20 0.55
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ATM Q13315 1/20 0.37
LMNA P02545 1/20 0.35
HCAR2 Q8TDS4 3/20 0.34
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30604742 0.97 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL93462 0.97 TSHR (0.84) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL2912109 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL15163252 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL1165263 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10508670 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL15163059 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
Ammonia Solution, Strong SCHEMBL27352657 0.94 TSHR (0.80) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL4602612 0.89 TSHR (1.00) TSHRALDH1A1TP53HIF1AHSD17B10
Propane SCHEMBL6904776 0.89 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688082-B1 COMPOSITIONS COMPRISING A TIN-BASED CATALYST AND TITANIUM DIOXIDE FOR MOISTURE CURE OF SILANE-FUNCTIONALIZED ETHYLENIC POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-08 EP disclosed
EP-3643741-B1 COATED CONDUCTOR WITH VOLTAGE-STABILIZED INNER LAYER DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP disclosed
US-11319425-B2 Compositions comprising a tin-based catalyst and titanium dioxide for moisture cure of silane-functionalized ethylenic polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-03 US disclosed
US-20210147653-A1 COMPOSITIONS COMPRISING A TIN-BASED CATALYST AND TITANIUM DIOXIDE FOR MOISTURE CURE OF SILANE-FUNCTIONALIZED ETHYLENIC POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2021-05-20 US disclosed
CN-104822367-B Silicone-modified polyolefins in personal care applications 陶氏环球技术有限责任公司 2021-01-12 CN disclosed
EP-3688082-A1 COMPOSITIONS COMPRISING A TIN-BASED CATALYST AND TITANIUM DIOXIDE FOR MOISTURE CURE OF SILANE-FUNCTIONALIZED ETHYLENIC POLYMERS Dow Global Technologies LLC (US) 2020-08-05 EP disclosed
EP-3643741-A1 COATED CONDUCTOR WITH VOLTAGE-STABILIZED INNER LAYER Dow Global Technologies LLC (US) 2020-04-29 EP disclosed
US-10622117-B2 Polymeric compositions with voltage stabilizer additive UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2020-04-14 US disclosed
EP-3395874-B1 COATED CONDUCTOR WITH VOLTAGE-STABILIZED INNER LAYER DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-11 EP disclosed
US-20190269599-A1 SILICON-CONTAINING POLYOLEFINS IN PERSONAL CARE APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-05 US disclosed
WO-2012044521-A1 POLYMERIC COMPOSITIONS WITH VOLTAGE STABILIZER ADDITIVE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2012-04-05 WO disclosed
WO-2012044499-A1 METHOD FOR MANUFACTURING FLEXIBLE MULTILAYER ELECTRICAL ARTICLES WITH IMPROVED LAYER ADHESION DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
EP-2367878-A1 CATALYST SYSTEM FOR MOISTURE CURE OF ETHYLENE-VINYLSILANE COPOLYMERS Dow Global Technologies LLC (US) 2011-09-28 EP disclosed
WO-2011034836-A1 PROCESS FOR PRODUCING CROSSLINKED, MELT-SHAPED ARTICLES UNION CARBIDE CHEMICAL & PLASTICS TECHNOLOGY LLC (US) 2011-03-24 WO disclosed
WO-2011034838-A1 CROSSLINKED, MELT-SHAPED ARTICLES AND COMPOSITIONS FOR PRODUCING SAME UNION CARBIDE CHEMILCALS & PLASTICS TECHNOLOGY LLC (US) 2011-03-24 WO disclosed
WO-2011034833-A2 PROCESS FOR MAKING CROSSLINKED INJECTION MOLDED ARTICLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2011-03-24 WO disclosed
US-20100297374-A1 In Situ Moisture Generation and Use of Polyfunctional Alcohols for Crosslinking of Silane-Functionalized Resins DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-25 US disclosed
WO-2010074920-A1 CATALYST SYSTEM FOR MOISTURE CURE OF ETHYLENE-VINYLSILANE COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-01 WO disclosed
WO-2010074925-A1 IN-SITU CATALYST AND MOISTURE GENERATION FOR CROSSLINKING OF SILANE-FUNCTIONALIZED POLYOLEFINS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-01 WO disclosed
US-20100160471-A1 Catalyst System for Moisture Cure of Ethylene-Vinylsilane Copolymers DOW GLOBAL TECHNOLOGIES INC. 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269599-A1 SILICON-CONTAINING POLYOLEFINS IN PERSONAL CARE APPLICATIONS SPTAN1, CUTA, SPG11 TSHR 3365/4885ALDH1A1 3153/4885TP53 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.