Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 6/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686052 | 0.88 | CES2 (0.42) | CES2GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL32686053 | 0.88 | CES2 (0.42) | CES2GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL32686158 | 0.83 | CES2 (0.38) | CES2GSK3BDYRK1ASYKHPGD | |
| SCHEMBL32685912 | 0.82 | CES2 (0.40) | CES2LIPCRETCCNCCDK8 | |
| SCHEMBL32686060 | 0.82 | CES2 (0.40) | CES2LIPCRETCCNCCDK8 | |
| SCHEMBL32686180 | 0.82 | CES2 (0.40) | CES2LIPCRETCCNCCDK8 | |
| SCHEMBL32685949 | 0.80 | CES2 (0.43) | CES2RETCCNCCDK8HPGD | |
| SCHEMBL32686140 | 0.80 | CES2 (0.43) | CES2RETCCNCCDK8HPGD | |
| SCHEMBL32686066 | 0.80 | CES2 (0.43) | CES2RETCCNCCDK8HPGD | |
| SCHEMBL31315329 | 0.78 | DYRK1A (0.45) | WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |