Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 6/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686288 | 1.00 | CBLB (0.34) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL25179561 | 0.88 | KDR (0.33) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL30605871 | 0.83 | CBLB (0.44) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL30605903 | 0.83 | CBLB (0.44) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL29841564 | 0.83 | CBLB (0.44) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL25178861 | 0.81 | CBLB (0.43) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL29841539 | 0.81 | CBLB (0.43) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL30891990 | 0.80 | CBLB (0.36) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL30891986 | 0.80 | CBLB (0.36) | CBLBKDRPLK4ROCK2NTRK1 | |
| SCHEMBL25183023 | 0.80 | ADRB2 (0.36) | CBLBKDRPLK4ROCK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |