Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.41 |
| ▸ | CBL | P22681 | 18/20 | 0.41 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22851384 | 0.91 | CBLB (0.46) | CBLBCBLCBLC | |
| SCHEMBL22832670 | 0.91 | CBLB (0.46) | CBLBCBLCBLC | |
| SCHEMBL22832669 | 0.91 | CBLB (0.46) | CBLBCBLCBLC | |
| SCHEMBL22832997 | 0.87 | CBLB (0.41) | CBLBCBLCBLC | |
| SCHEMBL32686579 | 0.86 | CBLB (0.39) | CBLBCBLCBLC | |
| SCHEMBL25179648 | 0.85 | CBLB (0.44) | CBLBCBL | |
| SCHEMBL30374080 | 0.85 | CBLB (0.44) | CBLBCBL | |
| SCHEMBL32686300 | 0.84 | CBLB (0.40) | CBLBCBLCBLC | |
| SCHEMBL25183642 | 0.84 | CBLB (0.40) | CBLBCBLCBLC | |
| SCHEMBL25183728 | 0.84 | CBLB (0.38) | CBLBCBLCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |