SCHEMBL32687119

SCHEMBL32687119

C=CC(F)(F)O[C@@H]1[C@@H](OCOCCOC)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(-c2cncs2)cc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.36
▸ CD38 P28907 6/20 0.32
▸ HCRTR1 O43613 1/20 0.31
▸ HCRTR2 O43614 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687336 0.94 GPR119 (0.36) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687771 0.92 GPR119 (0.38) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687522 0.90 GPR119 (0.36) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687139 0.89 GPR119 (0.38) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687603 0.89 GPR119 (0.36) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687018 0.89 IKBKB (0.31) —
SCHEMBL32687085 0.89 HDAC1 (0.31) —
SCHEMBL32687122 0.88 GPR119 (0.35) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687764 0.87 GPR119 (0.39) GPR119CD38HCRTR1HCRTR2
SCHEMBL32687234 0.87 GPR119 (0.38) GPR119CD38HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 GPR119 3997/4885CD38 2044/4885HCRTR1 4584/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS GPR119 3752/4885CD38 1590/4885HCRTR1 3614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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