SCHEMBL32687226

SCHEMBL32687226

Fc1cc(-c2cncs2)ccc1I

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DYRK1A Q13627 2/20 0.42
▸ CD38 P28907 15/20 0.42
▸ DYRK2 Q92630 1/20 0.38
▸ DYRK1B Q9Y463 1/20 0.38
▸ HDAC4 P56524 1/20 0.38
▸ PRMT5 O14744 1/20 0.38
▸ WDR77 Q9BQA1 1/20 0.38
▸ CHEK1 O14757 1/20 0.35
▸ CHEK2 O96017 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273966 0.85 DYRK1A (0.45) DYRK1ACD38DYRK2DYRK1BHDAC4
SCHEMBL32687454 0.80 DYRK1A (0.41) DYRK1ACD38DYRK2DYRK1BHDAC4
SCHEMBL30987723 0.75 SLC22A12 (0.47) DYRK1ACD38HDAC4CHEK1CHEK2
SCHEMBL27272888 0.75 SLC22A12 (0.47) DYRK1ACD38HDAC4CHEK1CHEK2
SCHEMBL17643727 0.74 CD38 (0.53) DYRK1ACD38DYRK2DYRK1BHDAC4
SCHEMBL32671911 0.74 CD38 (0.53) DYRK1ACD38DYRK2DYRK1BHDAC4
SCHEMBL26260195 0.74 DYRK1A (0.49) DYRK1ACD38DYRK2DYRK1BPRMT5
SCHEMBL7915410 0.74 CD38 (0.49) DYRK1ACD38DYRK2DYRK1BHDAC4
SCHEMBL28279469 0.74 PIK3CD (0.43) DYRK1ACD38HDAC4PRMT5WDR77
SCHEMBL1864798 0.73 CYP11B1 (0.43) DYRK1ACD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 DYRK1A 1128/4885CD38 2044/4885DYRK2 1077/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS DYRK1A 3010/4885CD38 1590/4885DYRK2 3514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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