SCHEMBL32687454

SCHEMBL32687454

Fc1cc(-c2cncs2)ccc1Br

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DYRK1A Q13627 2/20 0.41
▸ CD38 P28907 13/20 0.41
▸ HDAC4 P56524 1/20 0.40
▸ PRMT5 O14744 1/20 0.40
▸ WDR77 Q9BQA1 1/20 0.40
▸ HDAC8 Q9BY41 1/20 0.38
▸ KIF11 P52732 1/20 0.37
▸ DYRK2 Q92630 1/20 0.37
▸ DYRK1B Q9Y463 1/20 0.37
▸ CYP11B1 P15538 1/20 0.37
▸ CYP11B2 P19099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273966 0.83 DYRK1A (0.45) DYRK1ACD38HDAC4PRMT5WDR77
SCHEMBL32687226 0.80 DYRK1A (0.42) DYRK1ACD38HDAC4PRMT5WDR77
SCHEMBL999315 0.77 HDAC8 (0.46) DYRK1ACD38HDAC4HDAC8DYRK2
SCHEMBL27272888 0.73 SLC22A12 (0.47) DYRK1ACD38HDAC4
SCHEMBL30987723 0.73 SLC22A12 (0.47) DYRK1ACD38HDAC4
SCHEMBL2299673 0.73 KIF11 (0.55) KIF11CYP11B1CYP11B2
SCHEMBL30667797 0.73 DYRK1A (0.50) DYRK1ACD38HDAC8DYRK2DYRK1B
SCHEMBL32671911 0.73 CD38 (0.53) DYRK1ACD38HDAC4DYRK2DYRK1B
SCHEMBL26683964 0.73 DYRK1A (0.50) DYRK1ACD38HDAC8DYRK2DYRK1B
SCHEMBL17643727 0.73 CD38 (0.53) DYRK1ACD38HDAC4DYRK2DYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 DYRK1A 1128/4885CD38 2044/4885HDAC4 3697/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS DYRK1A 3010/4885CD38 1590/4885HDAC4 3192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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