Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 4/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.82 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.82 |
| ▸ | DRD1 | P21728 | 3/20 | 0.82 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.82 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.82 |
| ▸ | HTR1A | P08908 | 2/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.82 |
| ▸ | DRD3 | P35462 | 2/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.82 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.82 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.82 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.82 |
| ▸ | HTR2C | P28335 | 2/20 | 0.82 |
| ▸ | HTR2B | P41595 | 2/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183503 | 1.00 | ABCB11 (0.82) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL5477299 | 0.96 | ABCB11 (0.82) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL30471867 | 0.96 | ABCB11 (0.82) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL5477290 | 0.95 | ABCB11 (0.90) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL30958564 | 0.95 | ABCB11 (0.90) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL3181827 | 0.94 | CYP3A4 (0.85) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| Benzene SCHEMBL7444141 | 0.93 | TBXA2R (0.70) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL34462108 | 0.93 | TBXA2R (0.70) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL16634960 | 0.93 | TBXA2R (0.70) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 | |
| SCHEMBL1610044 | 0.93 | TBXA2R (0.70) | ABCB11ADORA3TBXA2RADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132195-A1 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE | Esteve Química, S.A. (ES) | 2009-12-16 | — | — | EP | claimed |
| WO-2008119759-A1 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE | Esteve Química, S.A. (ES) | 2008-10-09 | — | — | WO | claimed |
| EP-1975167-A1 | Acetone solvate of phthaloyl amlodipine | ESTEVE QUIMICA, S.A. (ES) | 2008-10-01 | — | — | EP | claimed |
| EP-2132195-B1 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE | ESTEVE QUIMICA SA (ES) | 2010-06-16 | — | — | EP | disclosed |
| EP-2132195-A1 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE | Esteve Química, S.A. (ES) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008119759-A1 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE | Esteve Química, S.A. (ES) | 2008-10-09 | — | — | WO | disclosed |
| EP-1975167-A1 | Acetone solvate of phthaloyl amlodipine | ESTEVE QUIMICA, S.A. (ES) | 2008-10-01 | — | — | EP | disclosed |