SCHEMBL32689154

SCHEMBL32689154

COC(=O)COC1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.40
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 6/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 3/20 0.36
KMT2A Q03164 2/20 0.36
TDP1 Q9NUW8 2/20 0.34
GAA P10253 1/20 0.34
ALOX15 P16050 1/20 0.33
RAB9A P51151 1/20 0.33
APEX1 P27695 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
ESR2 Q92731 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688701 0.84 EPHX2 (0.35) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL13806131 0.81 KDM4E (0.38) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL31695329 0.76 KDM4E (0.30) KDM4ELMNAALDH1A1
SCHEMBL13902834 0.75 KDM4E (0.34) EPHX2KDM4ELMNA
SCHEMBL11908866 0.74 ALDH1A1 (0.57) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL32689211 0.74 KDM4E (0.39) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL5182162 0.74 KDM4E (0.42) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL32689094 0.73 EPHX2 (0.40) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL1087617 0.72 EPHX2 (0.41) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL1087620 0.72 EPHX2 (0.41) EPHX2KDM4ELMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 EPHX2 154/4885KDM4E 4643/4885LMNA 2153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.