Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 14/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22628138 | 1.00 | ATF4 (0.51) | ATF4FFAR4BACE1BACE2FFAR1 | |
| SCHEMBL19556471 | 0.91 | ATF4 (0.61) | ATF4 | |
| SCHEMBL19556220 | 0.87 | ATF4 (0.57) | ATF4 | |
| SCHEMBL22436924 | 0.85 | ATF4 (0.54) | ATF4 | |
| SCHEMBL22656657 | 0.84 | ATF4 (0.62) | ATF4 | |
| SCHEMBL19569557 | 0.84 | ATF4 (0.58) | ATF4 | |
| SCHEMBL19555896 | 0.83 | ATF4 (0.52) | ATF4 | |
| SCHEMBL19556515 | 0.81 | ATF4 (0.58) | ATF4BACE1 | |
| SCHEMBL22669058 | 0.80 | ATF4 (0.58) | ATF4 | |
| SCHEMBL22396907 | 0.80 | ATF4 (0.70) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |