SCHEMBL32689796

SCHEMBL32689796

O=C(O)CCc1cc(Cl)ccc1OC1CC1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 6/20 0.59
RBP4 P02753 1/20 0.46
PTGDR2 Q9Y5Y4 7/20 0.46
FFAR1 O14842 2/20 0.46
MAPT P10636 1/20 0.44
KMO O15229 1/20 0.44
PTGER2 P43116 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
RORC P51449 1/20 0.41
CHRM1 P11229 1/20 0.41
HRH1 P35367 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7433243 0.79 FFAR1 (0.50) PTGDR2FFAR1MAPTTDP1
SCHEMBL30819586 0.79 MAPT (0.51) PTGDRMAPTRORC
SCHEMBL19522397 0.78 KMT2A (0.49) PTGDRFFAR1MAPTTDP1CHRM1
SCHEMBL3813636 0.78 PTGDR (0.57) PTGDRRBP4PTGDR2FFAR1FFAR4
SCHEMBL31717890 0.76 PLAU (0.51) PTGDRKMOFFAR4
SCHEMBL30819610 0.75 SLC6A4 (0.40) PTGDR
SCHEMBL32689809 0.75 PTGDR (0.44) PTGDRPTGDR2FFAR1MAPTTDP1
SCHEMBL929640 0.74 GRIK1 (0.62) KMORORC
Hydrochloric Acid SCHEMBL2777981 0.74 PTGDR (0.53) PTGDRRBP4FFAR1HRH1FFAR4
SCHEMBL3405256 0.74 THRA (0.56) PTGDRPTGER2HRH1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed