Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.60 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.55 |
| ▸ | ULK1 | O75385 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 2/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251185 | 0.82 | ALK (0.63) | ALKZAP70EGFRULK1IGF1R | |
| SCHEMBL31251214 | 0.82 | EGFR (0.61) | ALKZAP70EGFRMAPK9MAPK10 | |
| SCHEMBL31251143 | 0.81 | EGFR (0.60) | ALKEGFRBRD4AURKAAURKB | |
| SCHEMBL25002639 | 0.79 | ALK (0.55) | ALKEGFRULK1IGF1RCDK9 | |
| SCHEMBL31251253 | 0.78 | IGF1R (0.66) | ALKEGFRULK1IGF1RCCNK | |
| SCHEMBL32690286 | 0.77 | IGF1R (0.67) | ALKEGFRMAPK9MAPK10ULK1 | |
| SCHEMBL32690393 | 0.76 | PTK2 (0.54) | ALKULK1IGF1RCDK9BRD4 | |
| SCHEMBL29747119 | 0.76 | ZAP70 (0.56) | ALKZAP70MAPK9MAPK10IGF1R | |
| SCHEMBL29746768 | 0.76 | ZAP70 (0.56) | ALKZAP70MAPK9MAPK10IGF1R | |
| SCHEMBL31251244 | 0.75 | EGFR (0.85) | ALKEGFRIGF1RINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085050-A1 | TRIPLE KINASE INHIBITORS | UNOGEN BIOTECH LTD (US) | 2026-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085050-A1 | TRIPLE KINASE INHIBITORS | ALK, ERBB2, ERBB3 | ALK 1/4885ZAP70 571/4885EGFR 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.