Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 12/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355406 | 0.82 | ITGAV (0.46) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL3131367 | 0.82 | CXCR4 (0.58) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL3135105 | 0.82 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL13355356 | 0.80 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL1817178 | 0.80 | CXCR4 (0.55) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL3133173 | 0.79 | ITGAV (0.51) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL13355445 | 0.78 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL13355164 | 0.78 | ITGB3 (0.56) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL13355442 | 0.78 | ITGB3 (0.59) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL3139006 | 0.76 | CXCR4 (0.51) | ITGAVITGB3ITGB6ITGB8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |