SCHEMBL3269459

SCHEMBL3269459

NCn1nc2ccccc2n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
HPGD P15428 4/20 0.42
MAPT P10636 6/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
USP2 O75604 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
HTT P42858 2/20 0.36
CXCR4 P61073 1/20 0.36
ALDH1A1 P00352 5/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35
UBE2T Q9NPD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6960374 0.80 MAPT (0.41) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL13817406 0.78 KDM4E (0.46) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL7151154 0.75 MAPT (0.41) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL8088119 0.75 MAPT (0.44) MAPTL3MBTL1CXCR4TLR8
SCHEMBL2534891 0.74 KDM4E (0.42) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL8745426 0.74 KDM4E (0.42) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL6229399 0.74 HTT (0.45) KDM4EHPGDMAPTL3MBTL1POLB
SCHEMBL366356 0.73 MAPT (0.46) MAPTCXCR4TLR8
SCHEMBL14944890 0.70 KDM4E (0.40) KDM4EHPGDMAPTL3MBTL1CYP1A2
SCHEMBL6229314 0.70 POLB (0.48) KDM4EHPGDMAPTL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689028-A1 LUBRICANT ADDITIVE COMPOSITION FOR ELECTRIC VEHICLE The Lubrizol Corporation (US) 2026-02-11 EP disclosed
WO-2025216922-A1 BORON CONTAINING AUTOMOTIVE GEAR OIL THE LUBRIZOL CORPORATION (US) 2025-10-16 WO disclosed
WO-2024206581-A1 LUBRICANT ADDITIVE COMPOSITION FOR ELECTRIC VEHICLE THE LUBRIZOL CORPORATION (US) 2024-10-03 WO disclosed
US-20150045263-A1 Lubricating Composition LUBRIZOL CORP (US) 2015-02-12 US disclosed
US-20100160191-A1 Lubricating Composition THE LUBRIZOL CORPORATION (US) 2010-06-24 US disclosed
EP-2197994-A1 LUBRICANTS THAT DECREASE MICROPITTING FOR INDUSTRIAL GEARS The Lubrizol Corporation (US) 2010-06-23 EP disclosed
EP-2066771-A2 LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-06-10 EP disclosed
US-20090093384-A1 Lubricants That Decrease Micropitting for Industrial Gears THE LUBRIZOL CORPORATION (US) 2009-04-09 US disclosed
WO-2009045979-A1 LUBRICANTS THAT DECREASE MICROPITTING FOR INDUSTRIAL GEARS THE LUBRIZOL CORPORATION (US) 2009-04-09 WO disclosed
WO-2008027883-A2 LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2008-03-06 WO disclosed