SCHEMBL327029

SCHEMBL327029

C=C(C)C(C)CC=CCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.46
KMT2A Q03164 1/20 0.46
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
F7 P08709 1/20 0.37
F3 P13726 1/20 0.37
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
FAAH O00519 2/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
LPAR2 Q9HBW0 2/20 0.33
LPAR3 Q9UBY5 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1783823 0.80 F7 (0.46) MEN1CYP3A4KMT2AFFAR1FFAR4
SCHEMBL1783825 0.80 F7 (0.46) MEN1CYP3A4KMT2AFFAR1FFAR4
SCHEMBL8827833 0.79 MEN1 (0.50) MEN1CYP3A4KMT2AFFAR1FFAR4
SCHEMBL1026928 0.76 F7 (0.50) KMT2AFFAR1FFAR4F7F3
SCHEMBL3076324 0.76 F7 (0.50) KMT2AFFAR1FFAR4F7F3
SCHEMBL585188 0.76 F7 (0.50) KMT2AFFAR1FFAR4F7F3
SCHEMBL20808603 0.74 TRPV1 (0.33) TRPV1
SCHEMBL17822453 0.74 TERT (0.48) MEN1CYP3A4KMT2AFFAR1FFAR4
SCHEMBL3879703 0.74 FFAR1 (0.42) MEN1CYP3A4KMT2AFFAR1FFAR4
SCHEMBL2120972 0.74 TSHR (0.40) MEN1CYP3A4KMT2AFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2590973-B1 SOLIFENACIN SALTS CRYSTAL PHARMA SAU (ES) 2016-08-31 EP disclosed
US-8765785-B2 Solifenacin salts CRYSTAL PHARMA, S.A.U. (ES) 2014-07-01 US disclosed
US-20130203804-A1 SOLIFENACIN SALTS CRYSTAL PHARMA, S.A.U. (ES) 2013-08-08 US disclosed
EP-2590973-A1 SOLIFENACIN SALTS Crystal Pharma S.A.U (ES) 2013-05-15 EP disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
WO-2012004264-A1 SOLIFENACIN SALTS RAGACTIVES, S.L.U. (ES) 2012-01-12 WO disclosed
WO-2010031408-A2 GEL COMPOSITIONS AARHUS UNIVERSITET (DK) 2010-03-25 WO disclosed