⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373214 | 0.82 | — | — | |
| SCHEMBL18037714 | 0.79 | LDHA (0.38) | — | |
| SCHEMBL28207990 | 0.76 | OR51E2 (0.30) | — | |
| SCHEMBL8030353 | 0.75 | KDM5B (0.56) | — | |
| SCHEMBL10601862 | 0.75 | — | — | |
| SCHEMBL10513495 | 0.73 | — | — | |
| Bicarbonate SCHEMBL28118993 | 0.71 | CRBN (0.38) | — | |
| Bicarbonate SCHEMBL27900905 | 0.71 | CRBN (0.38) | — | |
| Bicarbonate SCHEMBL27900906 | 0.71 | CRBN (0.38) | — | |
| SCHEMBL12967694 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218073-A1 | IMMUNOMODULATORY ANTI-CD73 ANTIBODIES AND USES THEREOF | CORVUS PHARMACEUTICALS, INC. | 2024-07-04 | — | — | US | disclosed |
| US-20240216495-A1 | COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIUM DIFFICILE | PFIZER (US) | 2024-07-04 | — | — | US | disclosed |
| EP-3705133-B1 | OSPA CHIMERAS AND USE THEREOF IN VACCINES | BAXALTA INC (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024127215-A2 | IMMUNOGENIC COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| US-20240189410-A1 | IMMUNOGENIC COMPOSITIONS AND METHODS FOR ELICITING AN IMMUNE RESPONSE AGAINST CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE | PFIZER (US) | 2024-06-13 | — | — | US | disclosed |
| CN-111629750-B | Compositions and methods for eliciting an immune response against clostridium difficile | 辉瑞公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2024097831-A1 | BIOREACTIVE PROTEINS CONTAINING UNNATURAL AMINO ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-05-10 | — | — | WO | disclosed |
| EP-4365196-A2 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF | Wyeth LLC (US) | 2024-05-08 | — | — | EP | disclosed |
| US-11952597-B2 | Compositions and methods relating to a mutant Clostridium difficile toxin | PFIZER INC. (US) | 2024-04-09 | — | — | US | disclosed |
| WO-2024073546-A2 | MYCOBACTERIUM T CELLS EPITOPES, MEGAPOOLS AND USES THEREOF | LA JOLLA INSTITUTE FOR IMMUNOLOGY (US) | 2024-04-04 | — | — | WO | disclosed |
| US-5070190-A | IMMUNOSTIMULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0425601-A1 | CARBOHYDRATEACRYL- AND METHACRYLCOPOLYMERS AND THEIR MANUFACTURE. | BIOCARB AB (SE) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990010023-A1 | CARBOHYDRATEACRYL- AND METHACRYLCOPOLYMERS AND THEIR MANUFACTURE | BIOCARB AB (SE) | 1990-09-07 | — | — | WO | disclosed |
| US-4855283-A | IMMUNE SYSTEM STIMULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0143385-B1 | PHOSPHORYLISED GLYCOSIL AMIDES, UREAS, CARBAMATES AND THIOCARBAMATES, METHOD FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1989-03-15 | — | — | EP | disclosed |
| US-4737488-A | Immune system-stimulating N-glycosylated ureas and carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |
| US-4686208-A | Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates and method of use | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0206037-A2 | Carbamates and ureas of N-(2-aminoacylamido-2-desoxy-hexosyl) amide, method for their preparation and their pharmaceutical use | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0206037-A2 | Carbamates and ureas of N-(2-aminoacylamido-2-desoxy-hexosyl) amide, method for their preparation and their pharmaceutical use | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0143385-A2 | Phosphorylised glycosil amides, ureas, carbamates and thiocarbamates, method for their preparation and their use | BAYER AG (DE) | 1985-06-05 | — | — | EP | disclosed |