SCHEMBL3270618

SCHEMBL3270618

CCCNCCC[Si](C)(C)N[Si](C)(C)CCCNCCC

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.43
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3270058 0.81 CA12 (0.50) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL2331806 0.76 TSHR (0.35) TSHRALDH1A1
SCHEMBL3270353 0.74 PAOX (0.42) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL29449239 0.74 TSHR (0.39) TSHRALDH1A1MEN1KMT2A
SCHEMBL26000091 0.73 PAOX (0.50) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL12002833 0.73 PAOX (0.41) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL1276412 0.73 CYP2C19 (0.62) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL2905152 0.73 CYP2C19 (0.62) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL1247661 0.73 TSHR (0.73) PAOXTSHRALDH1A1CYP2C19MEN1
SCHEMBL21385113 0.72 TSHR (0.44) TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1050782-B1 Developer for developing electrostatic image, process for production thereof and image forming method CANON KK (JP) 2013-02-20 EP disclosed
EP-0658819-B1 Toner and developer for developing electrostatic image, process for production thereof and image forming method CANON KK (JP) 2010-06-23 EP disclosed
EP-1022619-B1 Toner and image forming method CANON KK (JP) 2006-07-26 EP disclosed
US-6800368-B2 Image display medium FUJI XEROX CO., LTD. (JP) 2004-10-05 US disclosed
US-6541174-B1 Mixture of binder, solid wax and coloring or magnetic particles and lubricant; development electrostatic latent images CANON KABUSHIKI KAISHA (JP) 2003-04-01 US disclosed
US-20020044333-A1 Image display medium FUJI XEROX CO., LTD. (JP) 2002-04-18 US disclosed
EP-0713153-B1 Toner for developing electrostatic images, two component type developer, developing method, image forming method, heat fixing method, and process for producing toner CANON KK (JP) 2001-03-14 EP disclosed
US-6187496-B1 DEVELOPER MIXTURE INCLUDING SURFACE-LUBRICATED TONER PARTICLES COMPRISING HOMO OR CO-POLYSTYRENE AND/OR POLYESTER BINDER, SOLID WAX, COLORANT, LIQUID SILICONE OIL OR FLUOROCARBON LUBRICANT AS RELEASE AGENT CANON KABUSHIKI KAISHA (JP) 2001-02-13 US disclosed
US-6156471-A Toner and image forming method CANON KABUSHIKI KAISHA (JP) 2000-12-05 US disclosed
EP-1050782-A1 Toner and developer for developing electrostatic image, process for production thereof and image forming method CANON KABUSHIKI KAISHA (JP) 2000-11-08 EP disclosed
EP-1022619-A1 Toner and image forming method CANON KABUSHIKI KAISHA (JP) 2000-07-26 EP disclosed
US-6077638-A MIXTURE OF TONER PARTICLES, BINDER AND SOLID WAX CANON KABUSHIKI KAISHA (JP) 2000-06-20 US disclosed
US-5824442-A CONTROLLING DEVELOPMENT AND DEVELOPMENT FOR ELECTROSTATIC IMAGES WITH THIN FILMS CANON KABUSHIKI KAISHA (JP) 1998-10-20 US disclosed
US-5707770-A TITANIA OR ALUMINA PARTICLES SURFACE TREATED WITH A SILICON COMPOUND OR SILICONE OIL, IMPROVED PERFORMANCE IN HIGH HUMIDITY CANON KABUSHIKI KAISHA (JP) 1998-01-13 US disclosed
EP-0713153-A2 Toner for developing electrostatic images, two component type developer, developing method, image forming method, heat fixing method, and process for producing toner CANON KABUSHIKI KAISHA (JP) 1996-05-22 EP disclosed
EP-0658819-A2 Toner and developer for developing electrostatic image, process for production thereof and image forming method CANON KABUSHIKI KAISHA (JP) 1995-06-21 EP disclosed