⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327122 | 1.00 | — | — | |
| SCHEMBL20168561 | 1.00 | — | — | |
| SCHEMBL6873315 | 1.00 | — | — | |
| SCHEMBL8143836 | 1.00 | — | — | |
| SCHEMBL12763448 | 0.90 | GABRR1 (0.52) | — | |
| SCHEMBL24242945 | 0.86 | GABRR1 (0.45) | — | |
| SCHEMBL9244510 | 0.86 | GABRR1 (0.45) | — | |
| SCHEMBL9990687 | 0.86 | GABRR1 (0.45) | — | |
| SCHEMBL1934966 | 0.86 | GABRR1 (0.45) | — | |
| SCHEMBL12032751 | 0.86 | GABRR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171462-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| EP-4539840-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Neuron23, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-4486722-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Nico Therapeutics, Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-119137101-A | Compounds, compositions, and methods | 尼科治疗有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2023244788-A9 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| WO-2023244788-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023168298-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| CN-110088089-B | Benzyl amino pyridyl cyclopropane carboxylic acid, pharmaceutical composition and application thereof | 勃林格殷格翰国际有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-0220220-B1 | PROCESS OF PREPARING 2,2-DIBROMO-3-OXONITRILES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0220250-A1 | UTILIZATION OF NITRILES AS ANTIMICROBIAL AGENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-06 | — | — | EP | disclosed |
| EP-0220220-A1 | Process of preparing 2,2-dibromo-3-oxonitriles. | HENKEL KGAA (DE) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006254-A1 | UTILIZATION OF NITRILES AS ANTIMICROBIAL AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-11-06 | — | — | WO | disclosed |
| WO-1986006369-A1 | ANTI-MICROBIAL NITRILE AND ITS PRODUCTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-11-06 | — | — | WO | disclosed |
| US-4556409-A | CONTROLLING SOYBEAN GROWTH | EMERY INDUSTRIES INC. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4418202-A | HERBICIDES, PESTICIDES | EMERY INDUSTRIES, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| US-4380656-A | PESTICIDES, HERBICIDES | EMERY INDUSTRIES, INC. (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380656-A | PESTICIDES, HERBICIDES | EMERY INDUSTRIES, INC. (US) | 1983-04-19 | — | — | US | disclosed |
| US-4351842-A | N-Cyclopropylisoindolines | GLAXO LABORATORIES LIMITED (GB) | 1982-09-28 | — | — | US | disclosed |