Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271091 | 0.92 | CCR5 (0.73) | CCR5CCL5 | |
| SCHEMBL5102852 | 0.91 | CCR5 (0.69) | CCR5 | |
| SCHEMBL3273167 | 0.90 | CCR5 (1.00) | CCR5CCL5 | |
| SCHEMBL3270182 | 0.90 | CCR5 (0.90) | CCR5 | |
| SCHEMBL3273285 | 0.89 | CCR5 (0.77) | CCR5CCL5 | |
| SCHEMBL3269814 | 0.88 | CCR5 (0.76) | CCR5CCL5 | |
| SCHEMBL3271451 | 0.88 | CCR5 (0.75) | CCR5CCL5 | |
| SCHEMBL3277245 | 0.87 | CCR5 (0.75) | CCR5CCL5 | |
| SCHEMBL3270468 | 0.86 | CCR5 (0.84) | CCR5CCL5 | |
| SCHEMBL3269700 | 0.86 | CCR5 (1.00) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066674-B1 | OCTAHYDROPYRROLO [3, 4-C] PYRROLE DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2010-06-30 | — | — | EP | claimed |
| US-7625905-B2 | Octahydro-pyrrolo[3,4-c]pyrrole CCR5 receptor antagonists | ROCHE PALO ALTO LLC (US) | 2009-12-01 | — | — | US | claimed |