Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28191314 | 0.91 | MAPT (0.71) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL17371150 | 0.91 | NPC1 (0.61) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL25485 | 0.91 | POLB (0.64) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL9514686 | 0.88 | MAPT (0.58) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL854691 | 0.88 | MAPT (0.60) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL5923861 | 0.88 | MAPT (0.64) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL11781151 | 0.87 | MAPT (0.57) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL11215247 | 0.82 | CACNA1B (0.60) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL11782909 | 0.82 | MAPT (0.52) | MAPTGAAKMT2AL3MBTL1KDM4E | |
| SCHEMBL5907200 | 0.81 | NQO1 (0.64) | MAPTGAAKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425653-A | Preparation method of N, N' -di (p-ethoxyphenyl) -1, 4-phthalimide | 烟台盛凯伦化学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-1411927-B1 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | TECHNION RES & DEV FOUNDATION (IL) | 2010-06-30 | — | — | EP | disclosed |
| US-6939963-B2 | Method for the preparation of selectively-substituted corroles and new substituted corroles | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2005-09-06 | — | — | US | disclosed |
| US-20040180872-A1 | Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180872-A1 | Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole | EPOR, NR2E3, CBR1 | MAPT 4774/4885GAA 2353/4885KMT2A 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.