Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327376 | 0.88 | NPC1 (0.53) | PIM1MAPK14KDM4EALDH1A1TDP1 | |
| SCHEMBL2513836 | 0.85 | PIM1 (0.58) | PIM1KDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL19219055 | 0.77 | PIM1 (0.51) | PIM1KDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL1771328 | 0.76 | PIM1 (0.54) | PIM1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20455525 | 0.76 | CDK4 (0.49) | PIM1MAPK14TDP1NPC1RAB9A | |
| SCHEMBL29386286 | 0.76 | CDK4 (0.49) | PIM1MAPK14TDP1NPC1RAB9A | |
| SCHEMBL776048 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL6129041 | 0.75 | NPC1 (0.46) | PIM1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL12824407 | 0.74 | KDM4E (0.71) | KDM4EALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL22895342 | 0.73 | PIM1 (0.38) | PIM1KDM4EALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004293-A2 | INSECTICIDE AND FUNGICIDE ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |