Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327377 | 0.88 | PIM1 (0.50) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL2513836 | 0.81 | PIM1 (0.58) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL3694038 | 0.77 | DYRK1A (0.42) | CYP19A1PIM1MAPTKCNA5KCNH2 | |
| SCHEMBL19219055 | 0.77 | PIM1 (0.51) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL6535045 | 0.75 | KDM4E (0.67) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL776048 | 0.75 | KDM4E (0.67) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL22147393 | 0.73 | NPC1 (0.54) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL1771328 | 0.73 | PIM1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL11972746 | 0.71 | NPC1 (0.74) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL1181563 | 0.71 | KDM4E (0.88) | NPC1RAB9ACYP19A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004293-A2 | INSECTICIDE AND FUNGICIDE ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |