SCHEMBL3274058

SCHEMBL3274058

CC(C)=CCCC(C)=CC=NO

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 2/20 0.57
MEN1 O00255 2/20 0.54
CYP3A4 P08684 2/20 0.54
ALOX15 P16050 2/20 0.54
NR1I2 O75469 1/20 0.53
LMNA P02545 1/20 0.53
PGR P06401 1/20 0.53
MAPT P10636 2/20 0.52
UGT1A1 P22309 1/20 0.52
SQLE Q14534 6/20 0.50
ATM Q13315 1/20 0.48
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15257167 1.00 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL5323637 1.00 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL5323634 1.00 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL15255046 1.00 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL13870979 0.96 KMT2A (0.67) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL3275116 0.96 KMT2A (0.67) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL30096335 0.85 ALDH1A1 (0.55) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL15257168 0.82 KDM4E (0.44) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL28575170 0.80 NR1I2 (0.76) ALDH1A1KMT2AKDM4EMEN1CYP3A4
SCHEMBL25396940 0.78 ALDH1A1 (0.64) ALDH1A1KMT2AKDM4EMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112062691-B Citral phenylbutyric acid oxime ester compound and synthetic method and application thereof 中国农业科学院油料作物研究所 2022-12-09 CN claimed
CN-111763155-B Citral oxime ester compound and synthetic method and application thereof 中国农业科学院油料作物研究所 2022-11-25 CN claimed
CN-112062691-A Citral phenylbutyrate oxime ester compound and synthesis method and application thereof 中国农业科学院油料作物研究所 2020-12-11 CN claimed
CN-111763155-A Citral oxime ester compound and synthesis method and application thereof 中国农业科学院油料作物研究所 2020-10-13 CN claimed
EP-2825661-B1 PROCESS FOR PREPARING TERPENE NITRILES FROM TERPENE OXIMES EMPLOYING AN ALDOXIME DEHYDRATASE BASF SE (DE) 2016-05-18 EP claimed
US-9080191-B2 Method for biocatalytic production of nitriles from oximes and oxime dehydratases usable therein BASF SE (DE) 2015-07-14 US claimed
US-20130244298-A1 METHOD FOR BIOCATALYTIC PRODUCTION OF NITRILES FROM OXIMES AND OXIME DEHYDRATASES USABLE THEREIN BASF SE (DE) 2013-09-19 US claimed
EP-1705171-A1 Improved aromachemicals Flexitral, Inc. (US) 2006-09-27 EP claimed
US-5892092-A BY DEHYDRATION OF THE CORRESPONDING OXIME BASF AKTIENGESELLSCHAFT (DE) 1999-04-06 US claimed
JP-11147865-A None JP disclosed
CN-117643874-A Supported solid base catalyst and preparation method and application thereof 山东新和成药业有限公司 2024-03-05 CN disclosed
CN-113999138-B Method for rapidly synthesizing citral by using methyl heptenone 万华化学集团股份有限公司 2023-09-19 CN disclosed
CN-113899907-B Method for efficiently screening aflatoxin green prevention and control materials in one step and application thereof 中国农业科学院油料作物研究所 2023-06-27 CN disclosed
CN-112062691-B Citral phenylbutyric acid oxime ester compound and synthetic method and application thereof 中国农业科学院油料作物研究所 2022-12-09 CN disclosed
EP-0902012-A2 Process for the preparation of aliphatic, unsaturated nitriles BASF AKTIENGESELLSCHAFT (DE) 1999-03-17 EP disclosed
US-4371722-A Cyclic terpenoid amines, their preparation and uses SCM CORPORATION (US) 1983-02-01 US disclosed
US-4307255-A CYCLOLINALOOL USEFUL AS A FRAGRANCE OR CHEMICAL INTERMEDIATES FOR MAKING CAROTENOIDS SCM CORPORATION (US) 1981-12-22 US disclosed
US-4267366-A PREPARED BY CYCLIZATION OF THE CORRESPONDING ACYCLIC TERPENOID AMINE, SAID CYCLIC TERPENOID AMINES BEING REACTED WITH AN ANHYDRIDE TO FORM A TERPENOID ESTER SCM CORPORATION (US) 1981-05-12 US disclosed
US-4244890-A PREPARED BY CYCLIZATION OF NERYL AND GERANYL AMINES SCM CORPORATION (US) 1981-01-13 US disclosed
US-4179468-A Cyclic terpenoid onium salts, their preparation and uses SCM CORPORATION (US) 1979-12-18 US disclosed