Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275084 | 0.86 | S1PR1 (0.59) | S1PR1 | |
| SCHEMBL3273925 | 0.86 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL4618115 | 0.80 | S1PR1 (0.67) | S1PR1 | |
| SCHEMBL4619354 | 0.71 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL4619925 | 0.69 | S1PR1 (0.59) | S1PR1S1PR3 | |
| SCHEMBL3275517 | 0.68 | S1PR1 (0.42) | S1PR1GSK3B | |
| SCHEMBL20615395 | 0.67 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL4930133 | 0.67 | S1PR1 (0.69) | S1PR1S1PR3 | |
| SCHEMBL4617792 | 0.67 | S1PR1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL1797335 | 0.67 | S1PR1 (0.57) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087491-A1 | POLYCYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-08 | — | — | US | disclosed |
| CN-101522646-A | Oxadiazole derivatives having anti-inflammatory and immunosuppressive properties | NOVARTIS AG (CH) | 2009-09-02 | — | — | CN | disclosed |
| EP-2081916-A1 | OXADIAZOLE DERIVATIVES WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE PROPERTIES | Novartis AG (CH) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008037476-A1 | OXADIAZOLE DERIVATIVES WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE PROPERTIES | NOVARTIS AG (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087491-A1 | POLYCYCLIC COMPOUNDS | CD4, HLA-DRB1, MALT1 | S1PR1 357/4885GSK3B 2831/4885NPSR1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.