Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316168 | 0.91 | HPGD (0.67) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL5512773 | 0.83 | ESR1 (0.45) | HPGDKDM4EALDH1A1HSD17B10PGR | |
| SCHEMBL20411991 | 0.80 | HPGD (0.50) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL2252003 | 0.79 | GPR3 (0.57) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL15828753 | 0.79 | KDM4E (0.56) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL14460892 | 0.78 | HPGD (0.49) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL2311548 | 0.76 | HPGD (0.63) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL25058982 | 0.75 | HPGD (0.46) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL14721578 | 0.75 | HPGD (0.50) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL5527461 | 0.75 | PSEN1 (0.60) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134143-B2 | 2,7-carbazolenevinylene derivatives as novel materials in producing organic based electronic devices | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-03-13 | — | — | US | disclosed |
| US-20070176163-A1 | 2,7-Carbazolenevinylene derivatives as novel materials in producing organic based electronic devices | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2007-08-02 | — | — | US | disclosed |