Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827105 | 0.81 | KDM4E (0.51) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL3276460 | 0.78 | ALDH1A1 (0.52) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL8547012 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL27351338 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL1356985 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL24372107 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL5608955 | 0.77 | ALDH1A1 (0.50) | CYP1A2CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL11577421 | 0.76 | KDM4E (0.52) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL14672489 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL9950214 | 0.75 | ALDH1A1 (0.62) | CYP1A2CYP2C19KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | claimed |