SCHEMBL3276932

SCHEMBL3276932

CC1CCCC2(C1)CC2(C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
APLNR P35414 1/20 0.32
ALDH1A1 P00352 3/20 0.32
FFAR3 O14843 1/20 0.31
TRPA1 O75762 1/20 0.30
EP300 Q09472 1/20 0.30
HIF1A Q16665 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL10706379 0.75 CYP1A2 (0.53) CYP1A2LMNAAPLNRHIF1A
SCHEMBL3272005 0.74 FFAR3 (0.40) CYP1A2POLBLMNAAPLNRALDH1A1
SCHEMBL6265218 0.74 FFAR3 (0.40) CYP1A2POLBLMNAAPLNRALDH1A1
SCHEMBL5899588 0.73 CYP1A2 (0.45) CYP1A2
SCHEMBL18306290 0.73 CYP1A2 (0.52) CYP1A2LMNAAPLNRFFAR3HIF1A
SCHEMBL5806204 0.73 CYP1A2 (0.52) CYP1A2LMNAAPLNRFFAR3HIF1A
SCHEMBL18069837 0.73 CYP1A2 (0.52) CYP1A2LMNAAPLNRFFAR3HIF1A
SCHEMBL3270369 0.73 ALDH1A1 (0.41) CYP1A2LMNAALDH1A1
Hydrogen Peroxide SCHEMBL27513983 0.72 CYP1A2 (0.48) CYP1A2APLNRALDH1A1TRPA1
SCHEMBL6917387 0.72 CYP1A2 (0.50) CYP1A2LMNAAPLNRFFAR3HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687452-B2 2-(3,3-dimethylcyclohexyl)propionic acid ethoxycarbonylmethyl ester; 1,5,5-trimethylspiro[2.5]octane-1-carboxylic acid ethoxycarbonylmethyl ester; new powerful musk odorants GIVAUDAN SA (CH) 2010-03-30 US disclosed
US-20070225201-A1 Organic Compounds GIVAUDAN SA (CH) 2007-09-27 US disclosed