Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 9/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044567 | 0.85 | KAT6A (0.42) | KAT6ARORCMAPKAPK2MMP8NR2F2 | |
| SCHEMBL3277042 | 0.80 | KAT6A (0.39) | KAT6ARORCMAPKAPK2MMP8NR2F2 | |
| SCHEMBL2055339 | 0.80 | KAT6A (0.40) | KAT6ARORCMAPKAPK2NR2F2RAB9A | |
| SCHEMBL23484531 | 0.73 | CA12 (0.47) | KAT6ARORCMAPKAPK2CA12CA1 | |
| SCHEMBL3561771 | 0.71 | KAT6A (0.56) | KAT6ARORCCA12CA1CA9 | |
| SCHEMBL20642214 | 0.71 | KAT6A (0.56) | KAT6ARORCCA12CA1CA9 | |
| SCHEMBL12115551 | 0.70 | MEN1 (0.43) | KAT6ARAB9A | |
| SCHEMBL3762081 | 0.70 | F7 (0.39) | CA12CA1CA9RAB9A | |
| SCHEMBL6125423 | 0.70 | KAT6A (0.43) | KAT6AMAPKAPK2CA12CA1CA9 | |
| SCHEMBL3403454 | 0.68 | KAT6A (0.60) | KAT6ACA12CA1CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200987-A1 | ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | Boehringer Ingelheim International GmbH (DE) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009030715-A1 | ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |